Ahmed
Methocarbamol is a centrally acting muscle relaxant. It is commonly used in the treatment of patients with acute painful conditions arising from muscle spasms. It is available as oral tablets of 500 mg and 750 mg strength and as an injection for Intramuscular and intravenous use. It has an onset of action of about 30 … Read more
Aducanumab-avwa is the generic name of Aduhelm. It has been recently given accelerated FDA approval based on its effect on reducing beta-amyloid plaques in patients with Alzheimer’s disease. Aducanumab MOA – How does the drug act? Alzheimer’s disease is characterized by the aggregation of beta-amyloid plaques in the brain. Aducanumab is a human monoclonal IgG1 … Read more
Lorazepam vs Clonazepam is a comparison of the two commonly used benzodiazepines. Although, both can be used for sleep, seizures, anxiety, and panic disorders, there are slight differences. Lorazepam Vs Clonazepam Introduction: Lorazepam (Ativan) and clonazepam (Klonopin) are two medications used in the treatment of depression and anxiety disorders. Both of them belong to the … Read more
Leuprolide MOA (Mechanism of action of Leuprolide) is discussed here in detail. Leuprolide Acetate is used as monotherapy or in combination with norethindrone for the treatment of various conditions listed below: Leuprolide acetate monthly depot injection is used for the palliative treatment of advanced prostatic carcinoma. For the treatment and prevention of recurrence of Endometriosis. It … Read more
Linzess uses and MOA to relieve constipation is discussed here in detail. Linzess is the brand name of Linaclotide. It is distributed and marketed by Allergan as oral capsules in three different capsule strengths: 72 mcg oral capsules 145 mcg capsules 290 mcg oral capsules. Linzess Uses (Linaclotide uses): Linzess is used to treat: Chronic … Read more
Lucemyra side effects are primarily because of its mechanism of action. Lucemyra is the brand name of Lofexidine hydrochloride. It is the first FDA-approved treatment of opioid withdrawal that is unrelated to the opioid class of medicines. Briefly about the treatment of Opioid withdrawal: Opioid withdrawal symptoms may manifest as nausea, vomiting, sweating, hot and … Read more
Patiromer MOA is similar to Sodium Zirconium Cyclosilicate (Lokelma) and Sodium Polystyrene sulfonate (SPS, Kayexalate). These remove the excess potassium from the body. Patiromer (Veltassa), Sodium Zirconium Cyclosilicate (Lokelma), and Sodium Polystyrene Sulfonate (Kayexalate) are the three potassium binding resins that have a slightly different mechanism of action (MOA), however, all of them bind to … Read more
Plavix and Omeprazole are two very commonly used medications. Often these drugs are taken together since omeprazole is combined to avoid the gastrointestinal side effects associated with aspirin or clopidogrel. However, the FDA recommends avoiding these two drugs in combination because omeprazole may reduce the efficacy of Clopidogrel. What options do you have then? Which … Read more
Bempedoic acid is a novel class of medicine that has got FDA approval in February 2020. It is used to treat patients with hyperlipidemia who do not achieve their target lipid levels despite maximally tolerated doses of statins. Bempedoic acid Uses: It is approved for the treatment of patients who have an established cardiovascular atherosclerotic … Read more
Sacituzumab marketed by the brand name of Trodelvy (Gilead Sciences) is FDA approved for the treatment of patients with advanced breast cancer and urothelial cancer. Trodelvy mechanism of action in the treatment of these cancers is a little complicated to understand. It is therefore important to define a few terminologies before discussing the MOA of … Read more