Does Truqap (Capivasertib) Cause Hyperglycemia?

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Yes! In clinical trials, hyperglycemia was reported in about 58% of the patients. TRUQAP (Capivasertib) is the most recently approved medicine for the treatment of breast cancer. It is recommended for women with the following [Ref]: Hormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative, Locally advanced or metastatic breast cancer with One or … Read more

Linzess MOA: Mechanism of Action of Linaclotide

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Linzess MOA (Mechanism of action) is different from most other medications used to treat constipation and IBS (Irritable Bowel Syndrome) such as Miralax. Linzess (Linaclotide) is the first-in-class medicine that acts on the intestinal epithelial cells and stimulates the transmembrane Guanylate Cyclase 2C receptors (GC-2C). Activation of guanylate cyclase 2 C receptors results in the … Read more

Veltassa Drug Class, Indications, Mechanism of Action

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Veltassa belongs to the class of drugs called “potassium-binding resins”. Its actual name or medical name is Patiromer Sorbitex Calcium.  It binds to the dietary potassium that we ingest and prevents its absorption. In exchange, it releases its calcium, hence it is a calcium-exchange potassium-binding resin. Although very specific and a much safer option than … Read more

Zavegepant Nasal Spray (Zavzpret) for Migraine

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Zavegepant Nasal Spray (Zavzpret) is a small-molecule, competitive antagonist of the calcitonin gene-related peptide (CGRP) receptor, which is a target for the treatment of migraine. CGRP is a neuropeptide that is found in high levels in the trigeminal nerve, which is believed to play a role in migraine pathogenesis. CGRP exerts its effects on the vasculature, … Read more

BEOVU Indications: Brolucizumab Prevents Vision

BEOVU (Brolucizumab) indications

BEOVU Indications: Wet age-related macular degeneration Brand Name: Beovu Drug Name: Brolucizumab Date of FDA Approval: 8th Oct 2019 Manufacturer: Novartis Pharmaceuticals [Ref] BEOVU® (Brolucizumab-dbll) injection is a medication that has been recently approved by the FDA for the treatment of wet age-related macular degeneration (AMD). It is one of the new molecules that block … Read more

Nubeqa Mechanism of Action (Darolutamide MOA)

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Darolutamide MOA is discussed in this article. It is a recently approved chemotherapeutic drug for the treatment of prostate cancer. Drug Name: Darolutamide MOA Brand Name: Nubeqa The prostate is a prevalent malignancy that commonly affects elderly males. Most prostate cancers are responsive to hormones. A therapeutic objective is to impede their proliferation by inhibiting … Read more

Bexagliflozin Side effects: Brenzavvy

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Brenzavvy (Bexagliflozin) is a medication used to manage type 2 diabetes by reducing blood sugar levels through the elimination of excess glucose in the urine. While Brenzavvy can be an effective treatment option for many people, it’s important to be aware of the side effects of this medication. Understanding these side effects can help you … Read more

Trofinetide MOA (Mechanism of Action of Daybue)

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Trofinetide MOA (Mechanism of action): Trofinetide is a synthetic peptide that has been developed as a potential treatment for Rett syndrome, a rare neurodevelopmental disorder that affects mainly girls. The mechanism of action of Trofinetide (Trofinetide MOA) is not fully understood, but it is believed to involve several different pathways in the brain. One of … Read more

mTOR Inhibitor Everolimus (Afinitor): MOA, Side effects, Dose

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Novartis’ Afinitor (everolimus) was approved by the FDA on February 26, 2016, for the treatment of adult patients with unresectable, locally advanced or metastatic progressive, well-differentiated non-functional neuroendocrine tumors (NETs) originating from the gastrointestinal or lung areas. Afinitor, also known as everolimus, is a type of medication categorized as an mTOR inhibitor. It is available … Read more