Linzess MOA (Mechanism of action) is different from most other medications used to treat constipation and IBS (Irritable Bowel Syndrome) such as Miralax. Linzess (Linaclotide) is the first-in-class medicine that acts on the intestinal epithelial cells and stimulates the transmembrane Guanylate Cyclase 2C receptors (GC-2C). Activation of guanylate cyclase 2 C receptors results in the … Read more
Veltassa belongs to the class of drugs called “potassium-binding resins”. Its actual name or medical name is Patiromer Sorbitex Calcium. It binds to the dietary potassium that we ingest and prevents its absorption. In exchange, it releases its calcium, hence it is a calcium-exchange potassium-binding resin. Although very specific and a much safer option than … Read more
Zavegepant Nasal Spray (Zavzpret) is a small-molecule, competitive antagonist of the calcitonin gene-related peptide (CGRP) receptor, which is a target for the treatment of migraine. CGRP is a neuropeptide that is found in high levels in the trigeminal nerve, which is believed to play a role in migraine pathogenesis. CGRP exerts its effects on the vasculature, … Read more
BEOVU Indications: Wet age-related macular degeneration Brand Name: Beovu Drug Name: Brolucizumab Date of FDA Approval: 8th Oct 2019 Manufacturer: Novartis Pharmaceuticals [Ref] BEOVU® (Brolucizumab-dbll) injection is a medication that has been recently approved by the FDA for the treatment of wet age-related macular degeneration (AMD). It is one of the new molecules that block … Read more
Darolutamide MOA is discussed in this article. It is a recently approved chemotherapeutic drug for the treatment of prostate cancer. Drug Name: Darolutamide MOA Brand Name: Nubeqa The prostate is a prevalent malignancy that commonly affects elderly males. Most prostate cancers are responsive to hormones. A therapeutic objective is to impede their proliferation by inhibiting … Read more
Brenzavvy (Bexagliflozin) is a medication used to manage type 2 diabetes by reducing blood sugar levels through the elimination of excess glucose in the urine. While Brenzavvy can be an effective treatment option for many people, it’s important to be aware of the side effects of this medication. Understanding these side effects can help you … Read more
Adcetris (Brentuximab Vedotin) is a medication used to treat certain types of cancer, including Hodgkin lymphoma and a type of non-Hodgkin lymphoma called systemic anaplastic large cell lymphoma. It is an antibody-drug conjugate that works by targeting cancer cells and delivering a toxin to destroy them. While Adcetris has been shown to be effective in … Read more
Trofinetide MOA (Mechanism of action): Trofinetide is a synthetic peptide that has been developed as a potential treatment for Rett syndrome, a rare neurodevelopmental disorder that affects mainly girls. The mechanism of action of Trofinetide (Trofinetide MOA) is not fully understood, but it is believed to involve several different pathways in the brain. One of … Read more
Novartis’ Afinitor (everolimus) was approved by the FDA on February 26, 2016, for the treatment of adult patients with unresectable, locally advanced or metastatic progressive, well-differentiated non-functional neuroendocrine tumors (NETs) originating from the gastrointestinal or lung areas. Afinitor, also known as everolimus, is a type of medication categorized as an mTOR inhibitor. It is available … Read more
Tremelimumab is marketed by name, Imjudo. It is a CTLA-4 inhibitor that has been approved for the treatment of unresectable HCC and non-small-cell carcinoma. What is CTLA-4? CTLA-4 (cytotoxic T-lymphocyte-associated protein 4) is a protein receptor that is expressed on the surface of T-cells (a type of immune cell). It functions as a negative regulator … Read more