Linzess uses and MOA to relieve constipation is discussed here in detail. Linzess is the brand name of Linaclotide. It is distributed and marketed by Allergan as oral capsules in three different capsule strengths: 72 mcg oral capsules 145 mcg capsules 290 mcg oral capsules. Linzess Uses (Linaclotide uses): Linzess is used to treat: Chronic…
Lucemyra side effects are primarily because of its mechanism of action. Lucemyra is the brand name of Lofexidine hydrochloride. It is the first FDA-approved treatment of opioid withdrawal that is unrelated to the opioid class of medicines. Briefly about the treatment of Opioid withdrawal: Opioid withdrawal symptoms may manifest as nausea, vomiting, sweating, hot and…
Patiromer MOA is similar to Sodium Zirconium Cyclosilicate (Lokelma) and Sodium Polystyrene sulfonate (SPS, Kayexalate). These remove the excess potassium from the body. Patiromer (Veltassa), Sodium Zirconium Cyclosilicate (Lokelma), and Sodium Polystyrene Sulfonate (Kayexalate) are the three potassium binding resins that have a slightly different mechanism of action (MOA), however, all of them bind to…
Plavix and Omeprazole are two very commonly used medications. Often these drugs are taken together since omeprazole is combined to avoid the gastrointestinal side effects associated with aspirin or clopidogrel. However, the FDA recommends avoiding these two drugs in combination because omeprazole may reduce the efficacy of Clopidogrel. What options do you have then? Which…
Bempedoic acid is a novel class of medicine that has got FDA approval in February 2020. It is used to treat patients with hyperlipidemia who do not achieve their target lipid levels despite maximally tolerated doses of statins. Bempedoic acid Uses: It is approved for the treatment of patients who have an established cardiovascular atherosclerotic…
Sacituzumab marketed by the brand name of Trodelvy (Gilead Sciences) is FDA approved for the treatment of patients with advanced breast cancer and urothelial cancer. Trodelvy mechanism of action in the treatment of these cancers is a little complicated to understand. It is therefore important to define a few terminologies before discussing the MOA of…
Black fungus is a serious disease and infection occurring in COVID-19 patients means 100% death! Safe and cost-effective drug treatment of black fungus (also called black mold and mucormycosis) is almost nonexistent. Only three antifungal medicines are currently available to treat black fungus. The commonly used antifungal drugs such as itraconazole, fluconazole, and voriconazole are…
The Latest Treatment of IBS with Constipation is discussed here. It is important to treat concomitant anxiety and use adequate dietary fiber before initiating these novel drugs. IBS overview: Irritable Bowel Syndrome (IBS) is a very common condition that primarily affects young individuals. It is a chronic idiopathic condition that is defined as recurrent abdominal…
Semaglutide is a GLP-1 analog that is 94% identical to the endogenous human GLP-1. It is available in the form of injections as Ozempic and Wegovy and as oral medicine by the brand name of Rybelsus. It is used to treat patients with Diabetes Mellitus Type 2 as an adjunct to diet and exercise. Recently,…
The Treatment of Constipation with Medicines Including the Latest Drugs is discussed here. It is important to note that lifestyle modification including adequate water intake, regular exercise, and adequate fiber intake is essential before initiating treatment of constipation with medicines and drugs. Constipation definition: Constipation is the passage of stools that are either harder than…
