Ahmed
Rituximab Vs Infliximab is a comparison of the two drugs. Rituximab is a monoclonal antibody that targets CD-20 Positive B Lymphocytes While Infliximab is a TNF Inhibitor. Drug Description: Rituximab Vs Infliximab: Rituximab Infliximab Class Monoclonal type I CD20 antibody Tumor necrosis factor (TNF-alpha or TNF-α) blocker Chimeric Monoclonal IgG1 antibody Trade Names MabThera, Rixathon, … Read more
Biologics for Psoriasis are used in patients who have moderate to severe disease or are not responsive to conventional therapies. Biologics for psoriasis are both effective and tolerable. They have good short-term and long-term efficacy. The most common side effect associated with the use of biologics for psoriasis is the increased incidence of infections. TNF-alpha … Read more
TNF inhibitors are being increasingly used in the treatment of various immune-mediated diseases such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel diseases, and psoriasis. There are five tumor necrosis factor inhibitors available to treat rheumatoid arthritis and other immune-mediated diseases worldwide. Biosimilar versions of TNF inhibitors are now available in certain countries. Additional biosimilar agents … Read more
Nintedanib (Ofev) is a small tyrosine kinase inhibitor that is used to treat patients with idiopathic pulmonary fibrosis, interstitial lung disease in patients with systemic sclerosis, and non-small cell lung cancer. Overview of Nintedanib and its indications: Nintedanib (Ofev) is a small tyrosine kinase inhibitor that primarily targets platelet-derived growth factor receptors (PDGFR), Fibroblast growth … Read more
Simponi Vs Humira (Golimumab vs Adalimumab) is a comparison of the two novel TNF inhibitors. Both of these drugs are TNF (Tumor Necrosis Factor) Inhibitors. Their function is to reduce inflammation in different disease conditions. These two drugs will be compared based on the mechanism of action, dosage formulations, pharmacokinetics, and efficacy in different conditions. Indications … Read more
Lubiprostone is marketed by the brand name Amitiza. It is a locally acting drug that primarily activates the intestinal chloride channels and increases the fluid in the digested food, relieving constipation. Unlike Trulance and Linzess (Plecanatide and Linaclotide), Amitiza (Lubiprostone) acts on the chloride channels and activates them. Trulance and Linzess are drugs used for … Read more
Trulance VS Linzess (Plecanatide Vs Linaclotide) are two novel medicines that are being increasingly used to treat patients with chronic idiopathic constipation and Irritable bowel syndrome with predominant symptoms of constipation. Trulance Vs Linzess (Plecanatide Vs Linaclotide) What is Trulance? Trulance is the brand name of Plecanatide. It relieves constipation by acting as a guanylate … Read more
Dupilumab MOA (mechanism of action of Dupilumab) is discussed here. It inhibits IL-4 and IL-13 signaling pathways and IgE-mediated inflammation. Dupilumab (generic name) is available by the brand name of Dupixent (Regeneron Pharmaceuticals, Inc). It is used to treat patients with moderate to severe atopic dermatitis with or without concomitant use of topical corticosteroids. It … Read more
Simponi vs Enbrel is a comparison of the two TNF-inhibitors, Golimumab and Etanercept. Both Simponi (Golimumab) and Enbrel (Etanercept) aim to reduce the process of inflammation by decreasing the production of Interleukin-6 and Interleukin-8. Owing to their strong immune-modulatory effects, these drugs are commonly used to treat autoimmune rheumatic conditions like ankylosing spondylitis, psoriatic arthritis, … Read more
Rituximab VS Obinutuzumab is a comparison of the two monoclonal antibodies that target the CD-20 B-lymphocytes. Obinutuzumab is a newer generation anti-CD 20 monoclonal antibody with greater efficacy and immune suppression. Obinutuzumab is believed to be twice as effective as Rituximab Drug Description: Rituximab Obinutuzumab Targets: Monoclonal type I CD20 antibody Monoclonal type II CD20 … Read more