Sacubitril Valsartan (ARNI) – Entresto Mechanism of Action in HFrEF

entresto mechanism of action arni sacubitril valsartan angiotensin receptor neprilysin inhibitor

Sacubitril Valsartan is an angiotensin receptor-neprilysin inhibitor (ARNI in short). It is available by the brand names Entresto and Uperio. Entersto mechanism of action is unique and is especially recommended in patients with Heart Failure and reduced Ejection Fraction. Entresto is a combination of a neprilysin antagonist (Sacubitril) and an ARB (Valsartan). This combination drug was … Read more