Tofacitinib Mechanism of Action: Xeljanz MOA

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Tofacitinib is an oral Janus Kinase Inhibitor. Because of its unique and novel mechanism of action, it is one of the potent JAK Inhibitors. It was approved by the FDA in 2012. It is available in two formulations: Immediate Release as Xeljanz, and The Extended Release Oral Tablets as Xeljanz XR Tofacitinib is a Janus … Read more

Rinvoq (Upadacitinib) Mechanism of Action (MOA)

upadacitinib mechanism of action rinvoq

Upadacitinib is among the novel class of medicines with a unique mechanism of action (MOA). It is available by the brand name, Rinvoq that has been approved in 2019 by the FDA. Among the biological medications, it is one of the few medicines that are available as oral tablet formulations with once-daily dosing. Rinvoq Indications: … Read more

Trulicity Side effects: Depression, Mood Swings, Anxiety

Methocarbamol for anxiety and muscle spasms trulicity side effects

Trulicity side effects are primarily GI-related. Most patients develop nausea, vomiting, bloating, and abdominal fullness. Little is known about the neurological side effects of Trulicity. However, post-marketing reports of patients who have developed neurological side effects are being reported. Side effects of Semaglutide (Rybelsus, Ozempic, and Wegovy) What is Trulicity? Trulicity is the brand name … Read more

Tirzepatide Side effects and How to Manage Them

Tirzepatide side effects

Tirzepatide Side effects may range from mild gastrointestinal side effects to serious life-threatening pancreatitis and kidney failure. Like the GLP-1 agonists, Semaglutide, Liraglutide, Dulaglutide, etc, it primarily acts in the gastrointestinal tract. Hence, most of the GI side effects are related to the gastrointestinal tract. What is Tirzepatide? It is the first of its class … Read more

Sitagliptin Side effects (Januvia): Pancreatitis, Body Pains, & More

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Sitagliptin is a DPP-IV Inhibitor. It is a commonly used diabetes medicine. Sitagliptin side effects are usually mild in nature, however, severe anaphylaxis and pancreatitis have also been reported. For mild sitagliptin side effects, the dose may be reduced, or treatment may be withheld for a few days. However, in cases of severe side effects, … Read more