Drugs MOA discusses the mechanism of action of each drug
Upadacitinib is among the novel class of medicines with a unique mechanism of action (MOA). It is available by the brand name, Rinvoq that has been approved in 2019 by the FDA. Among the biological medications, it is one of the few medicines that are available as oral tablet formulations with once-daily dosing. Rinvoq Indications: … Read more
Aimovig is a drug that is used in the preventive treatment of migraine headaches. It has got a unique mechanism of action. Aimovig is the brand name of Erenumab that is available as 70 mg/ml monthly subcutaneous injections. It is primarily indicated to prevent and reduce the severity of migraine headaches in patients who have … Read more
Miralax is the brand name of Polyethylene Glycol. It is a commonly used drug used to relieve constipation and for bowel preparation before a colonoscopic procedure. Miralax MOA as to how it acts to relieve constipation is discussed here. What is Miralax? Miralax or polyethylene Glycol 3350 is an osmotic laxative. It is available in … Read more
Sacubitril Valsartan is an angiotensin receptor-neprilysin inhibitor (ARNI in short). It is available by the brand names Entresto and Uperio. Entersto mechanism of action is unique and is especially recommended in patients with Heart Failure and reduced Ejection Fraction. Entresto is a combination of a neprilysin antagonist (Sacubitril) and an ARB (Valsartan). This combination drug was … Read more
Dupilumab MOA (mechanism of action of Dupilumab) is discussed here. It inhibits IL-4 and IL-13 signaling pathways and IgE-mediated inflammation. Dupilumab (generic name) is available by the brand name of Dupixent (Regeneron Pharmaceuticals, Inc). It is used to treat patients with moderate to severe atopic dermatitis with or without concomitant use of topical corticosteroids. It … Read more
Leuprolide MOA (Mechanism of action of Leuprolide) is discussed here in detail. Leuprolide Acetate is used as monotherapy or in combination with norethindrone for the treatment of various conditions listed below: Leuprolide acetate monthly depot injection is used for the palliative treatment of advanced prostatic carcinoma. For the treatment and prevention of recurrence of Endometriosis. It … Read more
Linzess uses and MOA to relieve constipation is discussed here in detail. Linzess is the brand name of Linaclotide. It is distributed and marketed by Allergan as oral capsules in three different capsule strengths: 72 mcg oral capsules 145 mcg capsules 290 mcg oral capsules. Linzess Uses (Linaclotide uses): Linzess is used to treat: Chronic … Read more
Patiromer MOA is similar to Sodium Zirconium Cyclosilicate (Lokelma) and Sodium Polystyrene sulfonate (SPS, Kayexalate). These remove the excess potassium from the body. Patiromer (Veltassa), Sodium Zirconium Cyclosilicate (Lokelma), and Sodium Polystyrene Sulfonate (Kayexalate) are the three potassium binding resins that have a slightly different mechanism of action (MOA), however, all of them bind to … Read more
Sacituzumab marketed by the brand name of Trodelvy (Gilead Sciences) is FDA approved for the treatment of patients with advanced breast cancer and urothelial cancer. Trodelvy mechanism of action in the treatment of these cancers is a little complicated to understand. It is therefore important to define a few terminologies before discussing the MOA of … Read more