Dupilumab MOA (mechanism of action of Dupilumab) is discussed here. It inhibits IL-4 and IL-13 signaling pathways and IgE-mediated inflammation. Dupilumab (generic name) is available by the brand name of Dupixent (Regeneron Pharmaceuticals, Inc). It is used to treat patients with moderate to severe atopic dermatitis with or without concomitant use of topical corticosteroids. It … Read more
Simponi vs Enbrel is a comparison of the two TNF-inhibitors, Golimumab and Etanercept. Both Simponi (Golimumab) and Enbrel (Etanercept) aim to reduce the process of inflammation by decreasing the production of Interleukin-6 and Interleukin-8. Owing to their strong immune-modulatory effects, these drugs are commonly used to treat autoimmune rheumatic conditions like ankylosing spondylitis, psoriatic arthritis, … Read more
Rituximab VS Obinutuzumab is a comparison of the two monoclonal antibodies that target the CD-20 B-lymphocytes. Obinutuzumab is a newer generation anti-CD 20 monoclonal antibody with greater efficacy and immune suppression. Obinutuzumab is believed to be twice as effective as Rituximab Drug Description: Rituximab Obinutuzumab Targets: Monoclonal type I CD20 antibody Monoclonal type II CD20 … Read more
Cymbalta (Duloxetine) Vs Lyrica (Pregabalin) Vs Neurontin (Gabapentin) is a comparison of the three commonly used drugs in the treatment of patients with diabetic neuropathy, anxiety, depression, and low back pain. Cymbalta Vs Lyrica Vs Neurontin Duloxetine (Cymbalta) is prescribed for the treatment of patients with diabetic neuropathy, depression, and chronic pain. Lyrica (Pregabalin) is … Read more
Eliquis Vs Plavix is a comparison of the two commonly used blood thinners, Apixaban and Clopidogrel. Both drugs have different mechanisms of action and different indications. Generally speaking, Apixaban is an anticoagulant and Clopidogrel is a platelet inhibitor. Drug Description of Eliquis and Plavix: Eliquis (Apixaban) Eliquis generic name is Apixaban. It is a widely … Read more
Trulance Side effects are primarily confined to the gastrointestinal tract. Trulance is the brand name of Plecanatide, marketed and manufactured by Synergy Pharmaceuticals. It has got FDA approval in 2017 for the treatment of patients with chronic idiopathic constipation (CIC) and Irritable Bowel Syndrome with predominant symptoms of constipation (IBS-C). Trulance contains Plecanatide as the … Read more
Methocarbamol (Robaxin) is a centrally acting drug that is primarily used to relieve muscle spasms. It has not been studied in patients with anxiety, insomnia, and depression, since it does not have any effect on the GABA, serotonin, or nor-epinephrine central pathways. Primary Uses of Methocarbamol (Robaxin): Methocarbamol (Robaxin) is primarily used in the treatment … Read more
Methocarbamol is a centrally acting muscle relaxant. It is commonly used in the treatment of patients with acute painful conditions arising from muscle spasms. It is available as oral tablets of 500 mg and 750 mg strength and as an injection for Intramuscular and intravenous use. It has an onset of action of about 30 … Read more
Aducanumab-avwa is the generic name of Aduhelm. It has been recently given accelerated FDA approval based on its effect on reducing beta-amyloid plaques in patients with Alzheimer’s disease. Aducanumab MOA – How does the drug act? Alzheimer’s disease is characterized by the aggregation of beta-amyloid plaques in the brain. Aducanumab is a human monoclonal IgG1 … Read more
Lorazepam vs Clonazepam is a comparison of the two commonly used benzodiazepines. Although, both can be used for sleep, seizures, anxiety, and panic disorders, there are slight differences. Lorazepam Vs Clonazepam Introduction: Lorazepam (Ativan) and clonazepam (Klonopin) are two medications used in the treatment of depression and anxiety disorders. Both of them belong to the … Read more